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In some cases the cardiologist will have you perform hand squeezing exercises to help get more accurate test results. You will wait 30 – 90
minutes after this test at which time you will go for another set of pictures. It is important to avoid
caffeinated and decaffeinated products for 24 hours prior to your exam. The exam will be rescheduled if you
do not follow this request.
What is Persantine?
Persantine is a coronary vasodilator that is used as a diagnostic agent in nuclear stress testing. Persantine
works by increasing the blood vessel circumference of the coronary arteries (arteries that feed the heart) in
order to increase blood flow to the heart.
Persantine causes a 20% increase in heart rate and a mild but significant decrease in systolic and diastolic blood
pressure. Persantine is metabolized in the liver. The amount of Persantine you will be given is based on
your body weight. Side effects include chest pain/pressure, dizziness, headache, nausea, shortness of breath, or a warm and flushed feeling. Some patients experience a
burning or stinging sensation at their IV site because Persantine is more acidic than your blood. Persantine
is contraindicated in patients who have a hypersensitivity to this drug. Persantine can also cause
bronchospasms, so your doctor may order a different test for you if you have certain lung conditions. If you
do develop side effects to Persantine the cardiologist can use a drug called aminophylline to reverse your side
effects.
Download Persantine Nuclear Stress Test (Adobe PDF document)
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